Food and pharmaceutical coating composition,method of preparation and products so coated

Composition de revetement alimentaire et pharmaceutique, methode de preparation et produit ainsi enrobe

Abstract

Des revetements pharmaceutiques sous forme de dispersion aqueuse d'un polymere insoluble dans l'eau prepare par dissolution du polymere dans un solvant organique non miscible a l'eau, en emulsifiant la solution organique dans l'eau, eventuellement avec l'aide d'additifs, et en eliminant le solvant organique du systeme pour obtenir une dispersion aqueuse coloidale, ou presque coloidale, ou un latex de petites particules polymeres de memes dimensions qui sont appliquees sur des dosages pharmaceutiques a partir de tres charges. Les latex, qui offrent une resistance a la croissance des bacteries et des moisissures et, lorsqu'ils sont combines a des additifs selectionnes, donnent des compositions de revetement appropriees, conferant d'excellentes proprietes de protection et de liberation aux dosages pharmaceutiques.
Pharmaceutical coatings in the form of aqueous dispersion of a water insoluble polymer prepared by dissolving the polymer in a water immiscible organic solvent, emulsifying the organic solution in water, optionally with the aid of additives, and stripping the organic solvent from the system to provide a colloidal, or near colloidal, aqueous dispersion or latex of small, even sized polymeric particules which are applied to pharmaceutical dosages from highly loaded latices. The latexes, which display resistance to bacterial and mold growth and, when combined with selected additives, provides convenient, attractive coating compositions which afford excellent protection and varied release properties to pharmaceutical dosages.

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NO-Patent Citations (1)

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    See also references of EP 0020496A4

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