Disclosed is a large-power LED driving circuit. The large-power LED driving circuit comprises an input circuit and a power supply adjusting circuit. The input circuit comprises a fusible resistor, a rectifier diode and an n-type filter circuit which are successively connected. The output of the n-type filter circuit is connected with the input end of the power supply adjusting circuit, the power supply adjusting circuit comprises an LNK306P integrated power chip, the D pin of the LNK306P integrated power chip is connected with the output end of the n-type filter circuit, the S pin of the LNK306P integrated power chip is connected with an energy storage loop and a driving loop which are connected in parallel, the driving loop comprises a current-limiting protective resistor, a voltage-stabilizing circuit and an output filer circuit which are successively connected, the output of the output filter circuit is connected with the two ends of an LED, and the FB pin of the LNK306P integrated power chip is connected with a feedback circuit. By adopting the technical scheme, the circuit structure is simple, fewer components are used, the cost is quite low, the current output is stable, and the performance is reliable.